Drug-drug interactions have been investigated with rosuvastatin use among many of the common cyp-inhibiting and -inducing medications.

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rosuvastatin administration did not indicate a teratogenic effect in rats at 25 mg kg day or in rabbits 3 mg kg day doses equivalent to the mrhd of 40 mg day based on auc and body surface area, respectively .

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rosuvastatin had the least reduction of and would thus be regarded as the most effective; however, none of the values for the statins were significant.

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some of these medications include a statin cholesterol-lowering drug fluvastatin lescol , atorvastatin lipitor, caduet , pitavastatin livalo , lovastatin mevacor,advicor, altoprev , simvastatin zocor, vytorin,simcor or pravastatin pravachol ,rosuvastatin crestor , or colchicine.

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methods a probabilistic monte carlo simulation model based on data from jupiter the justification for the use of statins in prevention an intervention trial evaluating rosuvastatin was used to estimate the long-term cost-effectiveness of rosuvastatin 20 mg daily versus simvastatin or atorvastatin 40 mg for the prevention of cardiovascular death and morbidity.

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